منابع مشابه
Droplet microfluidics.
Droplet-based microfluidic systems have been shown to be compatible with many chemical and biological reagents and capable of performing a variety of "digital fluidic" operations that can be rendered programmable and reconfigurable. This platform has dimensional scaling benefits that have enabled controlled and rapid mixing of fluids in the droplet reactors, resulting in decreased reaction time...
متن کاملLiquid-in-gas Droplet Microfluidics
Here we demonstrate a novel concept of liquid-in-gas droplet microfluidics by using gas flow as the continuous phase for the production of liquid droplets. Within a specially configured co-flow microfluidic tubing device, a flow of liquid phase has been continuously dispersed into another outer stream of gas phase, producing discrete and monodisperse microdroplets. This process is robust and we...
متن کاملDroplet microfluidics for high-throughput biological assays.
Droplet microfluidics offers significant advantages for performing high-throughput screens and sensitive assays. Droplets allow sample volumes to be significantly reduced, leading to concomitant reductions in cost. Manipulation and measurement at kilohertz speeds enable up to 10(8) samples to be screened in one day. Compartmentalization in droplets increases assay sensitivity by increasing the ...
متن کاملDroplet-based pyrosequencing using digital microfluidics.
The feasibility of implementing pyrosequencing chemistry within droplets using electrowetting-based digital microfluidics is reported. An array of electrodes patterned on a printed-circuit board was used to control the formation, transportation, merging, mixing, and splitting of submicroliter-sized droplets contained within an oil-filled chamber. A three-enzyme pyrosequencing protocol was imple...
متن کاملA droplet-based pH regulator in microfluidics.
In this paper, we develop a strategy to form on-demand droplets with specific pH values. The pH control is based on electrolysis of water in microfluidics, and the produced hydrogen and hydroxyl ions are separated and confined in individual containers during the droplet generation, triggered by a pressure pulse. By tuning the applied voltages and pressure pulses, we can control on demand the pH...
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ژورنال
عنوان ژورنال: Science Bulletin
سال: 2019
ISSN: 2095-9273
DOI: 10.1016/j.scib.2019.08.006